标题： 脊髓损伤和中风运动、感觉和自主功能恢复的脑机接口植入手术感知 显示英文标题

标题： Perception of Brain-Computer Interface Implantation Surgery for Motor, Sensory, and Autonomic Restoration in Spinal Cord Injury and Stroke

摘要： （摘要）中风和脊髓损伤是可能在身体和社会心理领域显著影响幸存者生活质量的状况。这两种疾病通常会导致严重的运动和感觉障碍，尽管目前有可用的治疗方法，但这些障碍并不完全可逆。侵入性脑机接口（BCI）已成为一种有前景的方法，可以绕过损伤部位并潜在地恢复运动和感觉功能。然而，为了最大化这种技术的效用和参与者的满意度，必须评估参与者接受BCI的意愿，并将其置于功能目标和康复优先事项的背景下。因此，我们对一组中风（n=33）、脊髓损伤（n=37）以及两者兼有（n=1）的参与者进行了调查，以了解他们对侵入性脑电图（ECoG）基BCI的接受程度，以及评估他们的功能康复目标。总体而言，参与者表示如果能够恢复基本运动功能，包括上肢、步态、排便/排尿和感觉功能，他们愿意接受手术植入ECoG网格用于BCI技术。参与者接受前瞻性BCI植入的意愿与BCI提供的功能恢复水平之间没有相关性。同样，接受手术的意愿与参与者感知的康复优先事项和残疾程度之间也没有相关性。这些发现表明，无论残疾程度和康复优先事项如何，参与者都对侵入性BCI技术感兴趣，即使只能恢复基本功能。这样的观察结果意味着第一代商业侵入性BCI可能不需要广泛的功能就能获得采用。相反，这也引发了一种担忧，即中风和脊髓损伤队列中的参与者可能对这种技术过于热情，这可能导致医疗剥削的潜在风险。 显示英文摘要

摘要： (Abridged) Stroke and SCI are conditions that can significantly impact the QoL of survivors in both the physical and psychosocial domains. Both diseases often result in significant motor and sensory impairments that are not fully reversible despite current available therapies. Invasive BCIs have emerged as a promising means to bypass the site of injury and potentially restore motor and sensory function. However, to maximize the utility and participant satisfaction with such technology, participants' willingness to embrace BCIs must be assessed, and placed in context with functional goals and rehabilitative priorities. Hence, we conducted a survey of a cohort of stroke (n=33), SCI (n=37), and both (n=1) participants regarding their receptiveness to invasive ECoG-based BCIs as well as to assess their goals for functional rehabilitation. Overall, participants indicated a high level of willingness to undergo surgery to implant ECoG grids for BCI technology if basic motor functions, including upper extremity, gait, bowel/bladder, and sensory function were restored. There was no correlation between participant willingness to undergo a prospective BCI implantation and the level of functional recovery offered by the BCI. Similarly, there was no correlation between willingness to undergo surgery and the participants' perceived rehabilitative priorities and level of disability. These findings indicate that participants were interested in invasive BCI technology even if only basic functions can be restored, regardless of their level of disability and their rehabilitative priorities. Such observations imply that first generation commercial invasive BCIs may not need extensive functions to garner adoption. Conversely, it also raises a concern that participants from the stroke and SCI cohort may be overly enthusiastic about such technology, which poses potential risks for medical exploitation.