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Quantitative Biology > Biomolecules

arXiv:2502.03606 (q-bio)
[Submitted on 5 Feb 2025 (v1) , last revised 10 Feb 2025 (this version, v2)]

Title: Artificial Intelligence Approaches for Anti-Addiction Drug Discovery

Title: 抗成瘾药物发现的人工智能方法

Authors:Dong Chen, Jian Jiang, Zhe Su, Guo-Wei Wei
Abstract: Drug addiction is a complex and pervasive global challenge that continues to pose significant public health concerns. Traditional approaches to anti-addiction drug discovery have struggled to deliver effective therapeutics, facing high attrition rates, long development timelines, and inefficiencies in processing large-scale data. Artificial intelligence (AI) has emerged as a transformative solution to address these issues. Using advanced algorithms, AI is revolutionizing drug discovery by enhancing the speed and precision of key processes. This review explores the transformative role of AI in the pipeline for anti-addiction drug discovery, including data collection, target identification, and compound optimization. By highlighting the potential of AI to overcome traditional barriers, this review systematically examines how AI addresses critical gaps in anti-addiction research, emphasizing its potential to revolutionize drug discovery and development, overcome challenges, and advance more effective therapeutic strategies.
Abstract: 药物成瘾是一个复杂且普遍存在的全球性挑战,持续对公共健康构成重大威胁。传统方法在抗成瘾药物研发方面难以提供有效的治疗方案,面临高失败率、漫长的开发周期以及处理大规模数据的低效问题。人工智能(AI)已成为解决这些问题的变革性方案。通过先进的算法,AI 正在通过提升关键流程的速度和精确度来彻底改变药物发现过程。本文综述了AI在抗成瘾药物研发中的变革作用,包括数据收集、靶点识别及化合物优化等方面。通过强调AI克服传统障碍的潜力,本文系统地探讨了AI如何填补抗成瘾研究中的关键空白,突出其在推动药物发现与开发、解决难题以及推进更有效的治疗策略方面的潜力。
Subjects: Biomolecules (q-bio.BM)
Cite as: arXiv:2502.03606 [q-bio.BM]
  (or arXiv:2502.03606v2 [q-bio.BM] for this version)
  https://doi.org/10.48550/arXiv.2502.03606
arXiv-issued DOI via DataCite

Submission history

From: Dong Chen [view email]
[v1] Wed, 5 Feb 2025 20:49:02 UTC (3,896 KB)
[v2] Mon, 10 Feb 2025 18:47:02 UTC (3,878 KB)
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