标题： 带记忆的分子蜘蛛 显示英文标题

标题： Molecular Spiders with Memory

摘要： 由单链DNA片段构成“腿”的合成生物分子蜘蛛可以在同样覆盖有与腿DNA互补的单链DNA片段的表面上移动。 在实验实现中，当一条腿第一次从表面的片段上脱离时，它会改变该片段，随后与这些改变后的片段结合的腿结合得更弱。 受这些实验的启发，我们研究了沿着一维底物移动的蜘蛛，其腿在新访问的位点上的移动速度比在重新访问的位点上更慢。 对于随机游走（单腿蜘蛛）来说，这种减速不会影响长时间的行为。 然而，对于双足蜘蛛而言，这种减速会产生一种有效的偏向，使其更倾向于未访问的位点，蜘蛛的行为类似于激发游走。 令人惊讶的是，蜘蛛在新位点上的减速增加了扩散系数，并加速了已访问位点数量的增长。 显示英文摘要

摘要： Synthetic bio-molecular spiders with "legs" made of single-stranded segments of DNA can move on a surface which is also covered by single-stranded segments of DNA complementary to the leg DNA. In experimental realizations, when a leg detaches from a segment of the surface for the first time it alters that segment, and legs subsequently bound to these altered segments more weakly. Inspired by these experiments we investigate spiders moving along a one-dimensional substrate, whose legs leave newly visited sites at a slower rate than revisited sites. For a random walk (one-leg spider) the slowdown does not effect the long time behavior. For a bipedal spider, however, the slowdown generates an effective bias towards unvisited sites, and the spider behaves similarly to the excited walk. Surprisingly, the slowing down of the spider at new sites increases the diffusion coefficient and accelerates the growth of the number of visited sites.