标题： 更多发霉的数据：另一个支原体基因跨越硅屏障进入人类基因组 显示英文标题

标题： More Mouldy Data: Another mycoplasma gene jumps the silicon barrier into the human genome

摘要： 人类基因组序列数据库包含非常类似于支原体霉菌的DNA序列。 这些霉菌似乎不仅感染分子生物学实验室，而且实验人员从受污染的样本中将其提取出来，并作为人类序列插入到GenBank中。 至少有一个霉菌的EST（表达序列标签）已从公共数据库转移到商业工具（Affymetrix HG-U133 plus 2.0微阵列）。 我们报告了一个第二个例子（DA466599），并认为有必要清理基因组数据库，但担心目前的工具可能不足以捕捉已经跨越硅屏障的基因。 显示英文摘要

摘要： The human genome sequence database contains DNA sequences very like those of mycoplasma molds. It appears such moulds infect not only molecular Biology laboratories but were picked up by experimenters from contaminated samples and inserted into GenBank as if they were human. At least one mouldy EST (Expressed Sequence Tag) has transferred from public databases to commercial tools (Affymetrix HG-U133 plus 2.0 microarrays). We report a second example (DA466599) and suggest there is a need to clean up genomic databases but fear current tools will be inadequate to catch genes which have jumped the silicon barrier.