标题： 噪声诱导的生化网络亚稳态 显示英文标题

标题： Noise-induced metastability in biochemical networks

摘要： 细胞内生化反应表现出丰富的动力学现象，这些现象无法通过平均场速率方程和加性噪声的框架来解释。 在这里，我们表明，亚稳态的存在和截然不同的时间尺度是广泛一类自催化反应网络的一般特征，并且，这一事实可以被利用以获得解析结果。 后一点通过处理经典的Togashi-Kaneko反应得到证明，该反应在过去十年中一直难以进行理论分析。 显示英文摘要

摘要： Intra-cellular biochemical reactions exhibit a rich dynamical phenomenology which cannot be explained within the framework of mean-field rate equations and additive noise. Here, we show that the presence of metastable states and radically different timescales are general features of a broad class of autocatalyic reaction networks, and moreover, that this fact may be exploited to gain analytical results. The latter point is demonstrated by a treatment of the paradigmatic Togashi-Kaneko reaction, which has resisted theoretical analysis for the last decade.