标题： 磁偶极子不兼容相关伪影在定量磁化率成像中的应用 显示英文标题

标题： Dipole Incompatibility Related Artifacts in Quantitative Susceptibility Mapping

摘要： 定量敏感性映射（QSM）中的伪影被分析，以建立QSM反演算法的最佳设计标准。 磁场所数据被分解为两部分，偶极子兼容部分和不兼容部分。 偶极子兼容部分生成所需的无条纹解。 偶极子不兼容部分，包括噪声、离散化误差和各向异性源，生成由波传播器定义的伪影，其中B0场方向作为时间轴。 颗粒噪声引起条纹伪影，连续性误差同时引起条纹伪影和阴影伪影。 作为一个例子，基于截断的QSM算法由于截断期间偶极子核的偏差而固有地容易产生条纹伪影。 通过数值幻像和成像实验，比较了几种QSM方法，包括一种贝叶斯正则化方法和k空间截断方法，结果表明，具有结构先验的贝叶斯方法在图像质量和定量测量方面都具有优势。 显示英文摘要

摘要： Artifacts in quantitative susceptibility mapping (QSM) are analyzed to establish an optimal design criterion for QSM inversion algorithms. The magnetic field data is decomposed into two parts, dipole compatible and incompatible parts. The dipole compatible part generates the desired non-streaking solution. The dipole incompatible part, including noise, discretization error, and anisotropy sources, generates artifacts defined by a wave propagator with the B0 field direction as the time axis. Granular noise causes streaking and contiguous error causes both streaking and shadow artifacts. As an example, truncation-based QSM algorithms are inherently prone to streaking artifacts because of the deviation of the dipole kernel during truncation. Through numerical phantom and imaging experiments, several QSM methods, including a Bayesian regularization method and the k-space truncation methods, were compared to show that the Bayesian approach with a structural prior provides advantages in terms of both image quality and quantitative measures.