标题： 纤毛微生物的趋化性：有噪声和无噪声的情况 显示英文标题

标题： Chemotaxis of ciliated microorganisms: with and without noise

摘要： 生物系统如纤毛微生物能够对外部化学梯度做出反应，这一过程称为趋化性，这里使用手性滑动模型进行了研究。 该理论模型将微生物视为具有活性表面滑动速度的球形体。 在存在化学梯度的情况下，由于配体与身体表面受体的结合，微生物的内部信号网络被触发。 因此，滑动速度的系数会发生变化，导致身体所遵循的路径发生变化。 我们观察到，梯度的强度并不是唯一控制身体动力学的参数，适应时间在身体趋化性的成功中也起着非常重要的作用。 如果我们忽略配体-受体结合中的离散性，身体的路径是平滑的，而这种结合本质上是随机的。 在存在后者的情况下，路径不仅不规则，而且身体的动力学也会发生变化。 我们通过改变化学梯度的强度和适应时间来计算平均首次通过时间，以研究趋化性的成功率。 显示英文摘要

摘要： Biological systems like ciliated microorganisms are capable to respond to the external chemical gradients, a process known as chemotaxis which has been studied here using the chiral squirmer model. This theoretical model considers the microorganism as a spherical body with an active surface slip velocity. In presence of a chemical gradient, the internal signaling network of the microorganism is triggered due to binding of the ligand with the receptors on the surface of the body. Consequently, the coefficients of the slip velocity get modified resulting in a change in the path followed by the body. We observe that the strength of the gradient is not the only parameter which controls the dynamics of the body but also the adaptation time play a very significant role in the success of chemotaxis of the body. Path of the body is smooth if we ignore the discreteness in the ligand-receptor binding which is stochastic in nature. In presence of the later, the path is not only irregular but the dynamics of the body changes. We calculate the mean first passage time, by varying strength of the chemical gradient and adaptation time, to investigate the success rate of chemotaxis.