标题： 线虫运动和行为的拓扑数据分析 显示英文标题

标题： Topological data analysis of C. elegans locomotion and behavior

摘要： 我们将拓扑数据分析应用于线虫的行为，线虫是生物学中广泛研究的模式生物。 特别是，我们使用拓扑学来生成复杂行为的定量总结，该总结可应用于高通量数据。 我们的方法使我们能够区分和分类来自不同环境条件的视频，并我们分析了准确性和可解释性之间的权衡。 此外，我们提出了一种新的技术，以输入的形式可视化我们分析的输出。 具体而言，我们使用持续同调的代表性循环来生成典型行为的合成视频。 显示英文摘要

摘要： We apply topological data analysis to the behavior of C. elegans, a widely-studied model organism in biology. In particular, we use topology to produce a quantitative summary of complex behavior which may be applied to high-throughput data. Our methods allow us to distinguish and classify videos from various environmental conditions and we analyze the trade-off between accuracy and interpretability. Furthermore, we present a novel technique for visualizing the outputs of our analysis in terms of the input. Specifically, we use representative cycles of persistent homology to produce synthetic videos of stereotypical behaviors.