标题： 多块磁粒子成像中由时间重复分布的示踪剂引起的运动伪影抑制 显示英文标题

标题： Suppression of Motion Artifacts Caused by Temporally Recurring Tracer Distributions in Multi-Patch Magnetic Particle Imaging

摘要： 磁粒子成像是一种基于示踪剂的成像技术，用于以高空间和时间分辨率确定超顺磁性氧化铁纳米颗粒的空间分布。 由于生理限制，成像体积的大小受到限制，较大的体积通过移动物体和成像体积相对于彼此来覆盖。 这导致时间分辨率降低，当成像动态示踪剂分布时可能会产生运动伪影。 这种动态分布的一个常见来源是在体内实验中的心脏和呼吸运动，这些运动在良好近似下是周期性的。 我们提出了一种原始数据处理技术，将数据片段组合成对应于动态运动特定状态的虚拟帧。 该技术基于从旋转体模在两个不同旋转频率下获得的测量数据进行评估。 这些频率是从原始数据中确定的，无需重建，也无需额外的导航信号。 重建后的图像合理地表示了在几种不同运动状态中冻结的旋转体模，同时抑制了运动伪影。 显示英文摘要

摘要： Magnetic particle imaging is a tracer based imaging technique to determine the spatial distribution of superparamagnetic iron oxide nanoparticles with a high spatial and temporal resolution. Due to physiological constraints, the imaging volume is restricted in size and larger volumes are covered by shifting object and imaging volume relative to each other. This results in reduced temporal resolution, which can lead to motion artifacts when imaging dynamic tracer distributions. A common source of such dynamic distributions are cardiac and respiratory motion in in-vivo experiments, which are in good approximation periodic. We present a raw data processing technique that combines data snippets into virtual frames corresponding to a specific state of the dynamic motion. The technique is evaluated on the basis of measurement data obtained from a rotational phantom at two different rotational frequencies. These frequencies are determined from the raw data without reconstruction and without an additional navigator signal. The reconstructed images give reasonable representations of the rotational phantom frozen in several different states of motion while motion artifacts are suppressed.