标题： 相分离依赖的Janus脂质囊泡主动运动 显示英文标题

标题： Phase separation dependent active motion of Janus lipid vesicles

摘要： 活性胶体系统已成为未来微器件的有希望的候选者。 虽然传统设计已广泛利用了硬胶体的使用，但细胞启发结构的发展代表了实现自我调节和高度功能的人工微游动器的关键路径。 在本工作中，我们制造并驱动了在交流电场下展示可重构运动的Janus脂质囊泡。 巨单层囊泡（GUVs）在室温下发生自发相分离，导致具有两个不同脂质相的类似Janus的GUVs。 我们报告了通过平行电极之间的感应电荷电渗作用实现的Janus GUVs的自推进。 值得注意的是，受电场影响的脂质膜的流体性质导致了不对称-对称瞬态状态，从而产生了由结构域分析支持的运行-翻滚事件。 我们表征了与翻滚事件相关的增强的旋转扩散率，该扩散率与热重定向解耦。 最后，我们确定了这些囊泡的货物释放能力和多种形状编码的动态模式。 这种细胞启发结构为创建运动的人工细胞和可编程微游动器提供了一种替代途径。 显示英文摘要

摘要： Active colloidal systems have emerged as promising contenders for the future of microdevices. While conventional designs have extensively exploited the use of hard colloids, the advancement of cell-inspired architectures represents a pivotal path towards realizing self-regulating and highly functional artificial microswimmers. In this work, we fabricate and actuate Janus lipid vesicles demonstrating reconfigurable motion under an AC electric field. The giant unilamellar vesicles (GUVs) undergo spontaneous phase separation at room temperature leading to Janus-like GUVs with two distinct lipid phases. We report self-propulsion of the Janus GUVs via induced charge electroosmosis, in between parallel electrodes. Remarkably, the fluid nature of the lipid membrane affected by the electric field leads to asymmetry-symmetry transient states resulting in run-and-tumble events supported by structure domain analysis. We characterise an enhanced rotational diffusivity associated with tumble events, decoupled from thermal reorientation. Lastly, we identify cargo-release capabilities and a variety of shape-encoded dynamic modes in these vesicles. This cell-inspired architecture provides an alternative route for creating motile artificial cells and programmable microswimmers.