标题： 胶体和蛋白质中电荷不均匀性的各向异性DLVO相互作用 显示英文标题

标题： Anisotropic DLVO-like interaction for charge patchiness in colloids and proteins

摘要： 软物质和生物物质的行为和稳定性显著依赖于静电相互作用，因为当蛋白质和胶体等粒子分散在电解质溶液中时，它们会带电。 一种用于理解涉及静电相互作用的宏观现象的典型简化假设是粒子电荷的各向同性。 然而，无论是在自然情况下还是通过合成方式产生的电荷分布通常是不均匀的，这导致了复杂的粒子间相互作用景观和复杂的组装现象。 这些相互作用的基本复杂性催生了基于不同假设和不同程度简化的模型，这些模型可能模糊真实物理行为与由于选择特定静电模型而产生的伪影之间的界限。 在广泛使用的线性化泊松-玻尔兹曼理论基础上，我们提出了一种理论框架——通过连接不同的模型，提供了对非均匀带电粒子之间静电相互作用的稳健的DLVO类似描述。 仅匹配两种不同平均场模型的{\em 单粒子}属性，我们在广泛的系统参数范围内发现{\em 相互作用能}之间具有定量一致性。 我们的工作确定了一种融合非均匀带电粒子不同模型的策略，并为它们相互作用的可靠、准确且计算成本较低的描述铺平了道路。 显示英文摘要

摘要： The behaviour and stability of soft and biological matter depend significantly on electrostatic interactions, as particles such as proteins and colloids acquire a charge when dispersed in an electrolytic solution. A typical simplification used to understand bulk phenomena involving electrostatic interactions is the isotropy of the charge on the particles. However, whether arising naturally or by synthesis, charge distributions are often inhomogeneous, leading to an intricate particle-particle interaction landscape and complex assembly phenomena. The fundamental complexity of these interactions gives rise to models based on distinct assumptions and varying degrees of simplifications which can blur the line between genuine physical behaviour and artefacts arising from the choice of a particular electrostatic model. Building upon the widely-used linearized Poisson-Boltzmann theory, we propose a theoretical framework that -- by bridging different models -- provides a robust DLVO-like description of electrostatic interactions between inhomogeneously charged particles. By matching solely the {\em single-particle} properties of two different mean-field models, we find a quantitative agreement between the {\em pair interaction energies} over a wide range of system parameters. Our work identifies a strategy to merge different models of inhomogeneously charged particles and paves the way to a reliable, accurate, and computationally affordable description of their interactions.