标题： 张力依赖的DNA环形成时间的理论模型 显示英文标题

标题： Theoretical Models for Tension-Dependent DNA Looping Time

摘要： 张力对DNA环化的影响在过去已经通过实验和理论进行了研究。 然而，不同的理论模型得出了不同的预测，这使得它们的有效性存在不确定性。 我们简要回顾了这些模型的预测，并提出了一种新的模型，该模型在长半柔性链上与模拟结果表现出卓越的一致性。 此外，我们阐明了我们的结果与之前提出的两态模型之间的关系，突出了支撑我们框架的不同解释方法。 我们的研究结果提供了预测性见解，为未来的实验验证铺平了道路。 显示英文摘要

摘要： The influence of tension on DNA looping has been studied both experimentally and theoretically in the past. However, different theoretical models have yielded different predictions, leaving uncertainty about their validity. We briefly review the predictions of those models and propose a novel model that demonstrates exceptional agreement with simulations for long semiflexible chains. Additionally, we elucidate the relationship between our result and that of the previously proposed two-state model, highlighting the distinct interpretative approach that underpins our framework. Our findings offer predictive insights that pave the way for future experimental validation.