标题： 基于计算机模拟双平面血管造影的动脉瘤自我校准极线重建评估方法 显示英文标题

标题： Self-Calibrated Epipolar Reconstruction for Assessment of Aneurysms in the Internal Carotid Artery Using In-Silico Biplane Angiograms

摘要： 颅内动脉瘤（IA）的治疗依赖于使用双平面视图的血管造影引导。 然而，由于血管重叠和缩短，血流估计和装置尺寸测量通常会受到影响，这可能会掩盖关键细节。 本研究介绍了一种极线重建方法，利用常规获取的双平面血管造影数据来增强颈内动脉（ICA）和动脉瘤穹顶的三维渲染。 我们的方法旨在通过克服传统二维成像技术的局限性来改善手术指导。 本研究采用了三种ICA动脉瘤的三维几何结构来模拟虚拟血管造影。 这些血管造影是使用计算流体动力学（CFD）求解器生成的，随后使用锥形束几何结构模拟双平面血管造影。 通过在双平面视图中匹配对比剂随时间的位置来完成自校准。 特征匹配用于三角化和重建三维血管结构。 投影数据被用来优化三维估计，包括消除错误结构和椭圆拟合。 使用Dice-Sorensen系数评估了重建的准确性，将三维重建与原始模型进行比较。 所提出的极线重建方法在三个测试的动脉瘤模型中表现良好，相应的Dice-Sorensen系数分别为0.745、0.759和0.654。 错误主要是由于部分血管重叠引起的。 所有三个体积的平均重建时间约为10秒。 所提出的极线重建方法增强了三维可视化，解决了如投影引起的血管缩短等挑战。 该方法提供了一种解决IA可视化复杂性的解决方案，有望为治疗提供更准确的分析和装置尺寸。 显示英文摘要

摘要： The treatment of intracranial aneurysms (IA) relies on angiography guidance using biplane views. However, accurate flow estimation and device sizing for treatment are often compromised by vessel overlap and foreshortening, which can obscure critical details. This study introduces an epipolar reconstruction approach to enhance 3D rendering of the internal carotid artery (ICA) and aneurysm dome using routinely acquired biplane angiographic data. Our method aims to improve procedural guidance by overcoming the limitations of traditional two-dimensional imaging techniques. This study employed three 3D geometries of ICA aneurysms to simulate virtual angiograms. These angiograms were generated using a computational fluid dynamics (CFD) solver, followed by the simulation of biplane angiography using a cone-beam geometry. Self-calibration was accomplished by matching contrast media position as a function of time between biplane views. Feature-matching was used to triangulate and reconstruct vascular structures in 3D. The projection data was utilized to refine the 3D estimation, including elimination of erroneous structures and ellipse-fitting. The accuracy of the reconstructions was evaluated using the Dice-Sorensen coefficient, comparing the 3D reconstructions to the original models. The proposed epipolar reconstruction method generalized well across the three tested aneurysm models, with respective Dice-Sorensen coefficients of 0.745, 0.759, and 0.654. Errors were primarily due to partial vessel overlap. The average reconstruction time for all three volumes was approximately 10 seconds. The proposed epipolar reconstruction method enhanced 3D visualization, addressing challenges such as projection-induced vessel foreshortening. This method provides a solution to the complexity of IA visualization, with the potential to provide more accurate analysis and device sizing for treatment.