标题： Martini 3用于双稳态纳米机器的设计 显示英文标题

标题： Martini 3 application for the design of bistable nanomachines

摘要： 在我们之前的全原子分子动力学建模中，我们已经识别出几种折叠体，其纳米尺度行为类似于经典双稳态机器，即欧拉拱和杜芬振子。 然而，全原子分子动力学的时间限制使我们无法对长期行为进行全面研究，并促使我们开发一种粗粒度模型。 在这项工作中，我们总结了我们最近使用最广泛可用的方法称为Martini来开发此类模型的研究。 显示英文摘要

摘要： During our previous modeling using all-atom molecular dynamics, we have identified several foldamers whose nanoscale behavior resembles that of classic bistable machines, namely the Euler archs and Duffing oscillators. However, time limitations of the all-atom molecular dynamics prevent us from performing a full-scale investigation of long-time behavior and prompt us to develop a coarse-grained model. In this work, we summarize our recent research on developing such models using the most widely available method called Martini.