标题： 平衡多跳EPI用于加速笛卡尔MRF：螺旋MRF的替代方法 显示英文标题

标题： Balanced multi-shot EPI for accelerated Cartesian MRF: An alternative to spiral MRF

摘要： 本研究的主要目的是展示一种使用多段EPI读出的高加速笛卡尔MRF方案（即多段EPI-MRF）可以在足够短的扫描时间内生成高质量的多参数图，如T1、T2和质子密度（PD），其扫描时间与传统MRF相似。这种多段方法在遍历整个k空间轨迹时允许显著的欠采样，可以获得更好的信噪比，减少模糊，降低失真，并且相比现有的单段EPI-MRF实现，还可以用于收集更高分辨率的数据。生成的参数图与具有相同采集参数的加速螺旋MRF实现进行比较，以评估该方法的性能。此外，应用了一种迭代重建算法来提高参数图估计的准确性，并且也展示了EPI-MRF的快速收敛性。 显示英文摘要

摘要： The main purpose of this study is to show that a highly accelerated Cartesian MRF scheme using a multi-shot EPI readout (i.e. multi-shot EPI-MRF) can produce good quality multi-parametric maps such as T1, T2 and proton density (PD) in a sufficiently short scan duration that is similar to conventional MRF. This multi-shot approach allows considerable subsampling while traversing the entire k-space trajectory, can yield better SNR, reduced blurring, less distortion and can also be used to collect higher resolution data compared to existing single-shot EPI-MRF implementations. The generated parametric maps are compared to an accelerated spiral MRF implementation with the same acquisition parameters to evaluate the performance of this method. Additionally, an iterative reconstruction algorithm is applied to improve the accuracy of parametric map estimations and the fast convergence of EPI-MRF is also demonstrated.