标题： 成本高效的网络流行病学疫苗接种方案 显示英文标题

标题： Cost-efficient vaccination protocols for network epidemiology

摘要： 我们研究针对接触网络的接种方法——即以尽可能阻止疾病传播的方式移除节点——在成本效益方面的表现。此类协议的实际实施都会带来与接种本身以及网络信息收集相关的成本。我们认为，忽视这一点会导致对接种协议的错误评估。我们使用易感-感染-恢复模型——一种患者康复后具有免疫力的疾病通用模型——作为我们的疾病传播情景，并在实际网络和模型网络上分析疫情爆发。对于不同的相对成本，不同的协议占主导地位。对于高接种成本和低信息收集成本的情况，所谓的熟人接种是最具成本效益的。对于其他参数值，设计用于高效识别网络最大度数的协议最为有效。 显示英文摘要

摘要： We investigate methods to vaccinate contact networks -- i.e. removing nodes in such a way that disease spreading is hindered as much as possible -- with respect to their cost-efficiency. Any real implementation of such protocols would come with costs related both to the vaccination itself, and gathering of information about the network. Disregarding this, we argue, would lead to erroneous evaluation of vaccination protocols. We use the susceptible-infected-recovered model -- the generic model for diseases making patients immune upon recovery -- as our disease-spreading scenario, and analyze outbreaks on both empirical and model networks. For different relative costs, different protocols dominate. For high vaccination costs and low costs of gathering information, the so-called acquaintance vaccination is the most cost efficient. For other parameter values, protocols designed for query-efficient identification of the network's largest degrees are most efficient.