标题： 下一代电生理学的尖峰检测与分类扩展 显示英文标题

标题： Scaling Spike Detection and Sorting for Next Generation Electrophysiology

摘要： 可靠的动作电位检测与分选，即将每个检测到的动作电位分配到其起始神经元的过程，是分析神经元的细胞外电记录数据的重要步骤。 最近开发的大规模、高密度微电极阵列和探针产生的数据量和复杂性，使得同时记录数千个通道的数据，大大增加了这一任务在概念和计算上的难度。 本章总结并讨论了近期开发的解决这些挑战的方法，并探讨了算法验证以及检测和分选质量评估的重要方面。 显示英文摘要

摘要： Reliable spike detection and sorting, the process of assigning each detected spike to its originating neuron, is an essential step in the analysis of extracellular electrical recordings from neurons. The volume and complexity of the data from recently developed large scale, high density microelectrode arrays and probes, which allow recording from thousands of channels simultaneously, substantially complicate this task conceptually and computationally. This chapter provides a summary and discussion of recently developed methods to tackle these challenges, and discuss the important aspect of algorithm validation, and assessment of detection and sorting quality.