标题： 倒置六方相的全局小角散射数据分析 显示英文标题

标题： Global Small-Angle Scattering Data Analysis of Inverted Hexagonal Phases

摘要： 我们开发了一个全局分析模型，用于随机取向、完全水合的反向六方（H$_\text{II}$）相，这些相由水溶液中的多种两亲分子形成，包括膜脂。 该模型基于六方紧密排列棒状结构的结构因子以及散射长度密度（SLD）的组成模型，从而也能够分析位置弱相关H$_\text{II}$相。 为了优化可调参数，我们使用了贝叶斯概率理论，这比标准分析技术能更详细地检索参数相关性，从而实现现实的误差分析。 该模型应用于不同的磷脂酰乙醇胺，包括之前未报道的二C14:0和二C16:1磷脂酰乙醇胺的H$_\text{II}$数据。 提取的结构特征包括固有脂质曲率、碳氢链长度以及中性平面处的每脂面积。 显示英文摘要

摘要： We have developed a global analysis model for randomly oriented, fully hydrated inverted hexagonal (H$_\text{II}$) phases formed by many amphiphiles in aqueous solution, including membrane lipids. The model is based on a structure factor for hexagonally packed rods and a compositional model for the scattering length density (SLD) enabling also the analysis of positionally weakly correlated H$_\text{II}$ phases. For optimization of the adjustable parameters we used Bayesian probability theory, which allows to retrieve parameter correlations in much more detail than standard analysis techniques, and thereby enables a realistic error analysis. The model was applied to different phosphatidylethanolamines including previously not reported H$_\text{II}$ data for diC14:0 and diC16:1 phosphatidylethanolamine. The extracted structural features include intrinsic lipid curvature, hydrocarbon chain length and area per lipid at the position of the neutral plane.