标题： 使用超声波制造具有可控孔隙率的聚（ε-己内酯）3D支架 显示英文标题

标题： Fabrication of Poly (ε-Caprolactone) 3D scaffolds with controllable porosity using ultrasound

摘要： 3D打印已经取得了显著进展，使得可以使用各种材料制造物体。 最近的进展中，采用了聚焦超声波用于3D打印，以实现在声学透明材料内部打印。 在这里，我们介绍了一种选择性超声熔融（SUM）方法，用于混合水的聚（{\epsilon }-己内酯）（PCL）粉末的3D打印。 打印是通过机械移动聚焦超声换能器完成的。 打印件的微观结构和孔隙率通过显微计算机断层扫描（{\mu }CT）进行分析。 通过水渗透法以及让荧光微球穿过结构来确定打印样品的开放孔隙率。 通过在支架上接种NIH-3T3成纤维细胞，随后使用活/死荧光检测进行分析，证实了打印结构的细胞相容性。 并通过扫描电子显微镜（SEM）进行可视化。 我们证明了SUM是一种可行的技术，可以打印具有主动控制孔隙率的结构。这种方法为诸如熔融沉积建模（FDM）和材料喷射等方法提供了替代方案。 显示英文摘要

摘要： 3D printing has progressed significantly, allowing objects to be produced using a wide variety of materials. Recent advances have employed focused ultrasound in 3D printing, to allow printing inside acoustically transparent materials. Here we introduce a Selective Ultrasonic Melting (SUM) method for 3D printing of poly ({\epsilon}-caprolactone) (PCL) powder mixed with water. The printing was done by mechanically moving a focused ultrasound transducer. The microstructure and porosity of the prints were analyzed with micro-computed tomography ({\mu}CT). The open porosity of the printed samples was determined using the water intrusion method and by passing fluorescent microspheres through the structure. The cytocompatibility of the printed structures was confirmed by seeding NIH-3T3 fibroblast cells on the scaffolds, followed by analysis using live/dead fluorescent assay. and visualization using scanning electron microscopy (SEM). We demonstrated that SUM is a viable technique to print structures with active control of their porosity This method provides an alternative to methods such as fused deposition modelling (FDM) and material jetting.