标题： 基于全一次性无线贴片传感器的实时心电间隔监测 显示英文标题

标题： Real-Time ECG Interval Monitoring Using a Fully Disposable Wireless Patch Sensor

摘要： 心电图间期监测为心脏疾病的诊断提供了关键见解。 标准的12导联心电图通常被使用，然而由于当前的新冠疫情，迫切需要一种远程监测解决方案，以减少医护人员接触冠状病毒的风险。 本文介绍了一种可抛弃的无线贴片生物传感器（VitalPatch）及其相关平台功能，用于实时连续测量临床相关的心电图间期，包括PR间期、QRS持续时间、QT间期、Bazett公式校正的QT间期（QTb）以及Fridericia公式校正的QT间期（QTf）。 通过将VitalPatch的自动算法间期测量结果与12导联心电图设备的手动标注全球间期进行比较，验证了VitalPatch的性能，测试对象为30名受试者。 间期监测的准确性（以平均时间误差计算，即从全球间期中减去VitalPatch的测量值）分别为PR间期2.7+/-15.94毫秒，QRS持续时间-1.97+/-12.29毫秒，QT间期-14.6+/-12.97毫秒，QTb-15.33+/-14.11毫秒，QTf-15.08+/-13.69毫秒。 这些结果表明，在疫情期间，VitalPatch是一种可行的心电图间期测量解决方案，同时可以利用其远程监测功能。 显示英文摘要

摘要： ECG interval monitoring provides key insights into the diagnosis of cardiac diseases. The standard 12-lead ECG is generally used, however, because of the current COVID-19 pandemic there is a strong need for a remote monitoring solution which will reduce exposure of health care providers to coronavirus. This article presents a disposable wireless patch biosensor (VitalPatch) and associated platform functionalities for real-time continuous measurement of clinically relevant ECG intervals including PR interval, QRS duration, QT interval, corrected QT interval by Bazett (QTb), and corrected QT interval by Fridericia (QTf). The performance of the VitalPatch is validated by comparing its automated algorithm interval measurements to the manually annotated global intervals of the 12-lead ECG device in 30 subjects. The accuracy of interval monitoring (in terms of mean timing error calculated by subtracting the VitalPatch measurements from the global intervals) is 2.7+/-15.94 ms, -1.97+/-12.29 ms, -14.6+/-12.97 ms, - 15.33+/-14.11 ms, and -15.08+/-13.69 ms for PR interval, QRS duration, QT interval, QTb, and QTf, respectively. These results demonstrate that the VitalPatch is a viable solution for measuring ECG intervals while taking advantage of its remote monitoring feature during the pandemic.