标题： 动态全视野OCT的滚动相位调制模式 显示英文标题

标题： Rolling phase modulation regime for dynamic full field OCT

摘要： 动态全场光学相干断层扫描（DFFOCT）最近作为一种无标记的显微技术出现，由于其对细胞活动的敏感性，以及速度和分层能力，使其成为一种不可或缺的技术。 然而，DFFOCT图像的质量常常由于相位噪声和条纹伪影而下降。 在本研究中，我们提出了一种名为滚动相位（RP）DFFOCT的新实现方法，其中参考臂被缓慢扫描超过2$\pi$的量级。 我们从数学上和实验上证明了它在同时提取静态和动态对比度的同时，显示出更优的图像质量。 我们在猴视网膜离体样本上展示了RP DFFOCT，并证明了其更好地解析亚细胞结构的能力，包括核内活动。 显示英文摘要

摘要： Dynamic full-field optical coherence tomography (DFFOCT) has recently emerged as an invaluable label-free microscopy technique, owing to its sensitivity to cell activity, as well as speed and sectioning ability. However, the quality of DFFOCT images are often degraded due to phase noise and fringe artifacts. In this work, we present a new implementation named Rolling-Phase (RP) DFFOCT, in which the reference arm is slowly scanned over magnitudes exceeding 2$\pi$. We demonstrate mathematically and experimentally that it shows superior image quality while enabling to extract both static and dynamic contrast simultaneously. We showcase RP DFFOCT on monkey retinal explant, and demonstrate its ability to better resolve subcellular structures, including intranuclear activity.